Human Erythrocyte Prolidase and Prolidase Deficiency
نویسندگان
چکیده
منابع مشابه
Biochemical Basis of Prolidase Deficiency
Cultured skin fibroblasts or lymphoblastoid cells from eight patients with clinical symptoms of prolidase deficiency were analyzed in terms of enzyme activity, presence of material crossreacting with specific antibodies, biosynthesis of the polypeptide, and mRNA corresponding to the enzyme. There are at least two enzymes that hydrolyze imidodipeptides in these cells and these two enzymes could ...
متن کاملProlidase deficiency and systemic lupus erythematosus.
Two children with prolidase deficiency, an inborn error of proline metabolism, developed clinical and immunological abnormalities consistent with a diagnosis of systemic lupus erythematosus (SLE). The first child died from septicaemia, and SLE was only diagnosed during his terminal illness. As a result of this diagnosis his cousin, who was already known to have prolidase deficiency, was investi...
متن کاملSequential and combined treatment of prolidase deficiency leg ulcers
Background The Authors report a case of chronic cutaneous lesions in a patient affected by prolidase deficiency, a rare disorder inherited through an autosomal recessive gene (50 cases reported). The enzyme prolidase is widely distributed throughout the body and it is important in the recycling of proline and hydroxyproline. Among the clinical presentations, the most striking manifestation is t...
متن کاملProlidase deficiency: dento-facial aspects in a paediatric patient.
BACKGROUND Prolidase Deficiency (PD) is a rare hereditary disease consisting in developmental delay, mental retardation, facial dysmorphism, splenomegaly, recurrent pulmonary infections and skin lesions. CASE REPORT The present study reports a case of PD treated in the Paediatric Section of the Department of Dentistry and Surgery at the University of Bari. A special diagnostic and clinical ap...
متن کاملStudies on Prolidase Deficiency Defect in Collagen Metabolism
ISEMURA, M., HANYU, T., ONO, T., IGARASHI, R., SATO, Y., GEJYO, F., NAKAZAWA, R., MIYAKAWA, T., TAKAGI, T., KUBOKI, Y., and SASAKI, S. Studies on Prolidase Deficiency with a Possible Defect in Collagen Metabolism. Tohoku J. exp. Med., 1981, 134 (1), 21-28 Skin collagen of a female patient with prolidase deficiency was examined for the distribution of borohydridereducible cross-links and the pro...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1982
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198203000-00013